影片的故事背景设定在虫兽与人类20年持久战之后的一次偷袭。面对这一前所未有的灾难，人类战警挺身而出，与异形虫兽展开了一场生死搏斗，誓死守护人类家园。
一种神秘且邪恶的病毒袭击了位于丛林深处的某军事基地，它令被感染的人类惊魂失神，狂躁嗜血，大屠杀和血腥蔓延丛林之中。急救人员索尼娅（Hélène de Fougerolles 饰）和男友马克（Francis Renaud 饰）救出一名伤者，但是伤者身上出现的奇怪症状令他们恐慌不已。随车离开的女战士坚决要求抛弃伤者，她因此和索尼娅、马克发生争执。混乱中她乱枪击重伤者，而自己也死于枪战中。伤者的血喷溅到马克身上，使他受到病毒的感染。索尼娅独自驱车奔驰在大雪纷飞的崇山峻岭，带爱人寻找治疗和避难的场所。 在等待救援的过程中，马克的身体逐渐发生变化。面对正渐渐丧失人性的爱人，索尼娅不得不做出选择…
洛杉矶的一个家庭在历史上最大的灾难的汇合中分开了：一个超级火山、一次特大地震和一次大规模龙卷风。当世界经受住这场几乎世界末日的事件时，我们的英雄们必须坚持自己的技能和智慧来团结和生存下去。
12-year old dreamer Vlad likes telling fantastic stories about his courage to his summer camp friends, although he is a bit of a coward himself. But one day Vlad finds himself in a real adventure as he accidentally gets caught in a conflict between two alien forces. Shapeshifting Trashmen, descendants of an ancient alien civilization, try to disable electricity on the whole planet by deactivating the defensive shield that protects the Earth from an approaching solar wave. In this way they challenge the all-powerful and mysterious Energy that enabled humanity's technological progress and which we depend on more than ever. In this battle Vlad is helped by a transformer box called the Bobot, which holds the key to saving the world. While telling stories about fictional courage is easy, Vlad will find out that overcoming his fear in the real world is quite a challenge. Mankind's future lies solely in his hands.
